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Ministry

Period

Name of Assignment

Role

Person in Charge

Minister of Commerce (Previously, Ministry of Knowledge Economy)

2013.07.01 ~2016.05.31 (End)

Concurrent detection of protein multiple marker

Early diagnosis of lung cancer based on mass spectrometric analysis and development and test of prognosis diagnosis kit

Leading Company

Je-Hyun Baek

Chungcheong Metropolitan Area

2013.06.01~2015.04.30 (End)

Development of Darbepoetin-Alfa bio-similar to enter into global market

Participating Company

Je-Hyun Baek

High-Tech Medical Complex

2013.09.23 ~2016.09.22

Construction of entry support system for GLP (Good Laboratory Practice) and clinical test in protein medicine and medical supplies

Leading Company

Je-Hyun Baek

Ministry of Health and Welfare

2016.04.01 ~2020.12.31

Development of optimal culture system of stem cells using multi-omics technology

Participating Company

Je-Hyun Baek

 

1.

Comprehensive proteome analysis of the excretory/secretory proteins of Toxoplasma gondii. Won-Kyu Lee, Hye-JinAhn, Je-Hyun Baek, Yeon Gyu Yu and Ho-Woo Nam. Bull. Korean Chem. Soc. Oct 2014 (accepted)

2.

Reciprocal changes in phosphorylation and methylation of Mammalian brain sodium channels in response to seizures.Baek JH, Rubinstein M, Scheuer T, Trimmer JS. J Biol Chem. 2014 May 30;289(22):15363-73

3.

SWATH-based Comparative Proteomic Analysis of the Mycobacterium bovis BCG-Korea Strain. Won-Kye Lee, Je-Hyun Baek, Sung WeonRyoo, and Yeon Guy Yu. Bull. Korean Chem. Soc. 2014, 35(3) 933-937

4.

Exosomal Proteins in the Aqueous Humor as Novel Biomarkers in Patients with Neovascular Age-related Macular Degeneration. Kang GY, Bang JY, Choi AJ, Yoon J, Lee WC, Choi S, Yoon S, Kim HC, Baek JH, Park HS, Lim HJ, Chung H. J Proteome Res. 2014 Feb 7;13(2):581-95

5.

Increased 26S proteasome non-ATPase regulatory subunit 1 in the aqueous humor of patients with age-related macular degeneration. Lee H, Choi AJ, Kang GY, Park HS, Kim HC, Lim HJ, Chung H. BMB Rep. 2013 Dec 1.

6.

AMP-activated protein kinase phosphorylates CtBP1 and down-regulates its activity. Kim JH, Choi SY, Kang BH, Lee SM, Park HS, Kang GY, Bang JY, Cho EJ, Youn HD. BiochemBiophys Res Commun. 2013 Feb 1;431(1):8-13

7.

Analysis of the biochemical role of Lys-11 in polyubiquitin chain formation using quantitative mass spectrometry. Jung JW, Bae SJ, Kang GY, Kim KH, Yeo WS, Park SH, Seol JH, Yi EC, Kim KP. Rapid Commun Mass Spectrom. 2013 Jan 30;27(2):339-46

8.

Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice. Woo DH, Kim SK, Lim HJ, Heo J, Park HS, Kang GY, Kim SE, You HJ, Hoeppner DJ, Kim Y, Kwon H, Choi TH, Lee JH, Hong SH, Song KW, Ahn EK, Chenoweth JG, Tesar PJ, McKay RD, Kim JH. Gastroenterology. 2012 Mar;142(3):602-11

9.

Biomarker discovery and proteomic evaluation of cadmium toxicity on a collembolan species, Paronychiuruskimi (Lee). Son J, Lee SE, Park BS, Jung J, Park HS, Bang JY, Kang GY, Cho K. Proteomics. 2011 Jun;11(11):2294-307

10.

Precursor miR-886, a novel noncoding RNA repressed in cancer, associates with PKR and modulates its activity. Lee K, Kunkeaw N, Jeon SH, Lee I, Johnson BH, Kang GY, Bang JY, Park HS, Leelayuwat C, Lee YS. RNA. 2011 Jun;17(6):1076-89

 

Name of Patent

Application Number

Application Date

Registration Date

Separation or concentration method using mesoporous titanium dioxide

10-2006-0127133

2006-12-13

2008-08-26

Manufacturing method of mesoporous titanium dioxide structure for separation, concentration and analysis and relevant structures for the analysis

10-2006-0127132

2006-12-13

2008-08-26

New mass spectrometry analysis signal amplification technology

10-2008-0111446

2008-11-11

2012-04-10

Methods for diagnosis, treatment, composites for prevention and information about age-related macular degeneration

10-2011-0047026

2011-05-18

2014-07-22

Oligo ethylene thiol molecules which are replaced for heavy hydrogen and relevant manufacturing method

10-2011-0140499

2011-12-22

2014-06-19

Photodegradable mass indicating materials and relevant use

10-2014-0050964

2014-04-28

 2016-01-04

Exosome separation method from biological solution

10-2014-0050965

2014-04-28

 

An Exosome isolation method from sample for the proteomic research

10-2015-0058036

2015-04-24

 

Thiochromene type compounds and their use

10-2015-0073537

2015-05-27

 2016-05-31

Assay for diagnosis of diseases using mass tag compound and the use thereof

10-2016-0067720

2016-05-31

 

 

Name of Patent

Country

Application No. in Each country

Internal Application Date

Patent Registration Date

New mass spectrometry analysis signal amplification technology

PCT

(International Application No.: PCT/KR2009/001839)

China

200980112571.1

2009-04-10

2014-02-05

Japan

2011-503911

2009-04-10

2013-09-20

USA

12/937139

2009-04-10

2014-03-18

Europe

9729499.5

2009-04-10

2013-06-12

Photodegradable mass indicating materials and relevant use

PCT

(International Application No.: PCT/KR2015/004242)

Thiochromene type compounds and their use

PCT

(International Application No.: PCT/KR2015/006167)

 

1. Special contribution newsletter in molecular biology: How can we utilize proteomics?  Hyung Soon Park

 

1.

2015 Annual KDRA Workshop (Korea Drug Research Association). Nov. 2015

 

“CMC Issues in Biosimilars Development and Analytical Comparability” (speaker: Je-Hyun Baek, Ph.D)

2.

DK-Sciex Joint Seminar. Nov. 2015

 

"Quality Control of Biologics and HCP Analysis Using Data-Independent Acquisition" (speaker: Gum-Yong Kang, Ph.D)

3.

DK-Sciex Joint Seminar. Nov. 2015

 

"Glycosylated and PEGylated protein Analysis using Triple-TOF 5600 Mass spectrometry" (speaker: Je-Hyun Baek, Ph.D)

4.

The KNS Conference (The Korean Nutrition Society). Nov. 2015

 

"Introduction of recent trends and tips in proteomic study" (speaker: Je-Hyun Baek, Ph.D)

5.

Symposium of Breast Cancer Translational Research (Korean Breast Cancer Society). Sep. 2015

 

"Introduction to proteomics for cancer researchers" (speaker: Je-Hyun Baek, Ph.D)

6.

The KSMS Conference (Korean Society for Mass Spectrometry). Aug. 2015

 

"Feasibility study in proteotyping of formalin-fixed, paraffin-embedded (FFPE) tissue samples using miniaturized fractionation techniques:

application of DK-Tip series" (speaker: Je-Hyun Baek, Ph.D)

7.

BIML Workshop (Korean Society for Bioinfomatics and Systems Biology). Jun. 2015

 

"Bioinformatics for proteomics" (speaker: Je-Hyun Baek, Ph.D)

8.

The PSK Conference (The Pharmaceuatical Society of Korea). Apr. 2015

 

"State-of-the art characterization of biopharmaceuticals for QC/QA using advanced mass spectrometry" (speaker: Je-Hyun Baek, Ph.D)

9.

The KSMS Conference (Korean Society for Mass Spectrometry). Aug. 2014

 

“Mass spectrometric BIORECORDs using data independent acquisition (DIA): case studies of urine, plasma, and pleural effusion samples”

(speaker: Je-Hyun Baek, Ph.D)

10.

The KSMS Conference (Korean Society for Mass Spectrometry). Mar. 2014

 

“Characterization of protein therapeutics by advanced mass spectrometry” (speaker: Hyung Soon Park, Ph.D)

11.

The KSG Conference (Korean Society for Glycoscience). Jan. 2014

 

“Rapid and sensitive characterization of bacterial lipid A by high resolution mass spectrometry” (speaker: Hyung Soon Park, Ph.D)

12.

The KSBMB Conference (Korean Society for Biochemistry and Molecular Biology). Jan. 2014

 

“Mass spectrometric biorecords as a useful tool to diagnose human diseases” (speaker: Je-Hyun Baek, Ph.D)

13.

KBSI User Meeting. Nov. 2013

 

“High resolution MS2-based label free quantification using Triple-Tof 5600+ mass spectrometry [SWATH approach]” (speaker: Je-Hyun Baek, Ph.D)

14.

AB Sciex webinar. Oct. 2013

 

“Proteome wide quantification to increase sensitivity and reproducibility using SWATH approach” (speaker: Je-Hyun Baek, Ph.D)

15.

The KSMS Conference (Korean Society for Mass Spectrometry). Aug. 2013

 

“Proteome-wide quantification for large number of samples using SWATH approach” (speaker: Je-Hyun Baek, Ph.D)

16.

The KHUPO Conference (The Korean Human proteome Organization: proteomics new technology workshop. Jul. 2013

 

“Industrial approaches to the biomarkers and biologics: Roles of innovative proteomics” (speaker: Hyung Soon Park, Ph.D)

17.

The KHUPO Conference (The Korean Human Proteome Organization). Mar. 2013

 

“Quantitative analysis of protein lysine acetylation in gastric ancer using antibody-based Super SILAC approach” (speaker: Je-Hyun Baek, Ph.D)

18.

The Biologics World Korea Conference. Apr. 2012

 

“Quantitative and Qualitative Analysis of Post-Translational Modification including Glycan Analysis in Biologics” (speaker: Hyung Soon Park, Ph.D)

 
 
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